45-Day Guarantee.
Trimix Starter Kit.

No response? Get a 100% refund.

Injectable ED treatment for when pills aren't enough. Three medications that work directly where they're needed.

$429 with a savings of $248
  • Test vial of Trimix
  • Autoject applicator
  • 5ml vial of antidote
  • Additional vial of Trimix
Add Starter Kit to Cart
  • Fast, discreet
    shipping
  • Physician
    supervised
  • Secure & private
    care
Men's Direct RX Trimix starter kit: test vial, additional vial, antidote, Autoject applicator and alcohol pads

Trimix starter kit

Everything you need to get started.

A complete starter kit with medication, supplies and training from our team.

Test vial of TrimixFind your right dose with a test vial.
Autoject applicatorFor easy, precise application.
5ml vial of antidoteTo prevent priapism.
Additional vial of TrimixBased on your test vial results.
$429

with a savings of $248

Add Starter Kit to Cart

First-time Trimix patients. Prescription required.

45DAY Don't achieve a penetrable erection with Trimix?Return the starter kit and unused medication for a 100% refund. See full detailsHide details

The fine print

  1. 1

    You must attempt the product 4 times.

  2. 2

    Each of the first 3 attempts must be followed up with a Trimix Results Form, found in the Forms section at the bottom of MensDirectRX.com.

  3. 3

    Attempts 2, 3 and 4 must all follow the physician's suggested dose. This arrives by text and/or email within 24 hours of your Trimix Results Form submission.

  4. 4

    Trimix with zero results is very rare but can happen. These cases are considered user error, so please consult our office before your next attempt.

Return protocol

If, after 4 unsuccessful attempts, you decide to return the product:

  • Box up your remaining Trimix, the unopened antidote and the re-boxed Autoject applicator.

  • Ship via UPS or FedEx Ground to: LT Medical Group, 16301 NE 8th Street, Bellevue, WA 98008.

  • Ship within 45 days of your order's original arrival date, at your expense.

Once the package arrives at our office, the entire cost of your Trimix Starter Kit is refunded to your card.

Questions? Contact our office before your next attempt: (425) 201-0774

Erection lasting 4 hours or longer? Call 800-541-3946 for step-by-step instructions.

In-Person Trimix Exam

Bellevue, WA

$99
  • Doctor exam plus supervised test dose
  • See a response or 100% refund
  • Discreet, professional setting
Book Bellevue Visit

Free Consultation

Q&A with our team

  • Ask anything about injectable ED treatment
  • See if Trimix is right for you
  • Free and confidential
Get a Free Consultation

Trimix Options

Refills and supplies. Your physician sets your strength.

Trimix 100mcg5ml vial · about 25 doses

$599/vial

Add to Cart
Trimix 150mcg5ml vial · about 25 doses

$699/vial

Add to Cart
Trimix 300mcg5ml vial · about 25 doses

$799/vial

Add to Cart

How It Works

Simple. Safe. Effective.

  1. 1. Consult

    Book a $99 exam in Bellevue or a free consultation with our team.

  2. 2. Get your kit

    Your starter kit ships discreetly with everything you need, plus training.

  3. 3. Get results

    Follow your physician's dosing plan, with our video library and hotline on hand.

Dr. Nolan Noska

Physician oversight you can trust.

Dr. Nolan Noska, ND Medical Director
  • Medical director since 2016
  • Focused on hormone therapy and men's health
  • Personalized, discreet care
Read Dr. Noska's bio
Lesson 1 of 5

What is Trimix?

Trimix is a compounded injectable ED medication that combines three ingredients. Each one relaxes blood vessels and smooth muscle in a different way, so together they produce a firm, reliable erection.

  • Alprostadil: relaxes smooth muscle and widens arteries
  • Papaverine: relaxes muscle to increase blood flow
  • Phentolamine: blocks the signals that tighten blood vessels
  • Recommended by the AUA and Mayo Clinic
Lesson 2 of 5

Why Trimix works when pills don't

Pills depend on digestion and on your nerves sending the right signals. Trimix is injected directly where it's needed, so it bypasses the digestive tract and liver and doesn't rely on those nerve pathways.

That's why it's often used by men with diabetes, after prostate surgery, or anyone who hasn't gotten the results they wanted from oral medication.

  • 85-90% average success rate in clinical trials
  • Over 80% for men who failed oral medication
  • 75-85% after radical prostate surgery
  • Results usually appear within minutes
About those numbersSuccess rates as reported in published clinical trials. Individual results vary.
Lesson 3 of 5

How the injection works

It sounds intimidating, but most men describe only mild discomfort. The needle is very small, and an auto-injector applicator makes it quick.

Our team trains you in person or online: how to draw a dose, load the auto-injector and position it correctly. You also get our instructional video library and same-day phone or Zoom support.

  • Tiny, fine needle
  • Inject into the side of the shaft
  • Alternate sides each time
  • Auto-injector does the work
Lesson 4 of 5

Finding the right dose

Trimix comes in different strengths, measured by the amount of alprostadil. The right strength depends on your body and your goals, which is why it starts with an exam and a supervised test dose.

Your physician sets your strength and can adjust it over time. Never change your dose on your own.

  • $99 in-office exam with test dose
  • Strengths from 10mcg to 300mcg
  • 5ml vials, about 25 doses at 0.2 ml
  • Money back guarantee on the exam
Lesson 5 of 5

Safety, priapism and your antidote

The most important risk with Trimix is priapism: an erection that lasts 4 hours or longer. It's rare when you use the dose your physician sets, but you should always know what to do.

Starter kits include phenylephrine, the antidote, and Men's Direct RX runs a 24-hour priapism hotline.

  • Use only your prescribed dose
  • Follow your physician's limits on frequency
  • Rotate injection sites
  • Store as directed
Erection lasting 4+ hours?Call 800-541-3946 for step-by-step instructions, or seek emergency care.

Frequently Asked Questions

How quickly does Trimix work?

Results usually appear within minutes, making it one of the fastest options available.

What if it doesn't work for me?

The Starter Kit is covered by our 45-Day Guarantee. If you don't achieve a penetrable erection after 4 attempts that follow the guarantee steps, return the kit and unused medication for a 100% refund. See the full details above.

Is the injection painful?

Most men describe only mild discomfort with the very small needle used, and the Autoject applicator makes it quick.

How effective is Trimix compared to oral ED medication?

Trimix is often more effective, especially for men who did not respond well to oral medications.

Can Trimix be adjusted for different needs?

Yes. Our providers can change the dosage strength so it matches your specific goals.

Is Trimix safe to use long term?

When used under medical supervision, Trimix is considered safe for extended use.

Take control with Trimix.

Start with the starter kit, backed by our 45-day guarantee.

  • Discreet shipping
  • Physician supervised
  • Secure & private care
  • Serving men since 2015

Important Safety Information

Prescription required. Trimix (alprostadil, papaverine, phentolamine) is injected and must be used exactly as instructed by your physician. The most serious risk is priapism, an erection lasting 4 hours or longer, which is a medical emergency. If this happens, call the Men's Direct RX priapism hotline at 800-541-3946 or seek emergency care. Other side effects may include pain, bruising or scarring at the injection site. Tell your physician about blood thinners, bleeding disorders and all medications you take. Results vary.

Trimix exam$99
Book Exam